Minimal cut sets in biochemical reaction networks
By Steffen Klamt, Ernst Dieter Gilles. Bioinform., 2004
302 citations recorded by the source corpus.
Subfields: Molecular Biology
View Paper: https://www.semanticscholar.org/paper/6a2d654694a7aab3e1745b665f3b68e50e6e4ec5
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Molecular Biology
- Ernst Dieter Gilles
- J. Sáez-Rodríguez
- V. Schachter
- Pierre-Yves Bourguignon
- Maxime Durot
- Steffen Klamt
- Jonathan A. Lindquist
- Luca Simeoni
Citations in the corpus
- Structural and functional analysis of cellular networks with CellNetAnalyzer (2007, unknown): “The computation of MCSs has been revised; it relies now on the Berge algorithm known from the theory of minimal hitting sets [19,16] outper-forming the original algorithm introduced in [15] by about two orders of magnitudes.”
- A methodology for the structural and functional analysis of signaling and regulatory networks (2006, background): “Recently, the concept of minimal cut sets has been introduced for identifying targets in metabolic networks [28,29].”
- Genome-scale models of bacterial metabolism: reconstruction and applications (2008, methodology): “Given the combinatorial complexity of mixing several gene deletions, dedicated methods have been designed to analyze the effects of multiple deletions and applied to identify epistatic interactions between genes (Klamt & Gilles, 2004; Deutscher et al ., 2006, 2008; Imielinski & Belta, 2008).”
- Structure and dynamics of molecular networks: A novel paradigm of drug discovery: A comprehensive review (2012, unknown): “…where kinetic parameters are known, while flux balance analysis (FBA), flux-variability analysis (FVA) and elementary flux mode analysis are very useful methods to characterize systems-level metabolic responses (Fell, 1998; Cascante et al., 2002; Klamt & Gilles, 2004; Chavali et al., 2012).”