Physico-chemical stability of colloidal lipid particles.

By B. Heurtault, P. Saulnier, B. Pech, J. Proust, J. Benoit. Biomaterials, 2003

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Freeze-drying of nanoparticles: formulation, process and storage considerations. (2006, background): “However, due to their internal location in the studied particles, they were less susceptible to hydrolysis than external phospholipids [25].”
Importance of solid lipid nanoparticles (SLN) in various administration routes and future perspectives (2007, background): “…investigation of their structural properties, factors affecting their formation and storage stability, drug loading principles and drug release characteristics (Müller et al 2000; Mehnert and Mäder 2001; Müller et al 2002a; Müller et al 2002b; Heurtault et al 2003; Müller and Keck 2003; Uner 2006).”