Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration.

By A. Deczkowska, Hadas Keren-Shaul, A. Weiner, M. Colonna, M. Schwartz, Ido Amit. Cell, 2018

1,197 citations recorded by the source corpus.

Subfields: Immunology, Neurology

View Paper: https://www.semanticscholar.org/paper/df54bc5bbf7f04f66ed9c57e128ed71e9ba3dd10

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Immunology

1. M. Colonna
2. Florent Ginhoux
3. Mitchell A. Lazar
4. Eran Elinav
5. Y. Belkaid
6. Shizuo Akira
7. O. Harrison

In Neurology

1. M. Colonna
2. Florent Ginhoux

Citations in the corpus

• Lipid-associated macrophages control metabolic homeostasis in a Trem2-dependent manner (2019, background): “…of locally resident macrophages (Lavin et al., 2014; Okabe and Medzhitov, 2016), our findings suggest that the module of the Trem2-pathway may represent a conserved and general macrophage response for detection of extracellular pathogenic lipids across multiple tissues (Deczkowska et al., 2018).”
• Molecular and cellular mechanisms underlying the pathogenesis of Alzheimer’s disease (2020, background): “Recent studies identified a new microglial subtype termed “disease-associated microglia” (DAM) in animal models of AD [316].”
• ROS Generation in Microglia: Understanding Oxidative Stress and Inflammation in Neurodegenerative Disease (2020, background): “This expression profile concurs with other studies of DAM [10,37,78,124,194].”