Hepatitis C Virus-Encoded Enzymatic Activities and Conserved RNA Elements in the 3′ Nontranslated Region Are Essential for Virus Replication In Vivo

By A. Kolykhalov, K. Mihalik, S. Feinstone, Charles M. Rice. Journal of Virology, 2000

626 citations recorded by the source corpus.

Subfields: Epidemiology, Hepatology, Virology

View Paper: https://www.semanticscholar.org/paper/df4f0cf442f9ac5e846a336dbb7da794961137a8

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Epidemiology

1. Charles M. Rice
2. Brett D. Lindenbach Heinz-J

In Hepatology

1. Charles M. Rice
2. Brett D. Lindenbach Heinz-J
3. Ralf Bartenschlager

In Virology

1. Charles M. Rice
2. Brett D. Lindenbach Heinz-J

Citations in the corpus

• Flaviviridae :T he Viruses and Their Replication (2007, methodology): “These infectious clones have been used to show that all viral enzymes, the p7 gene, and correct 3′ end are essential for HCV replication in vivo (349,620,784).”
• Replication of hepatitis C virus. (2000, background): “It has a tripartite structure composed of a variable sequence following the stop codon of the ORF, a poly(U) tract of heterogeneous length and a highly conserved 98 nucleotide sequence essential for replication in vivo (Yanagi et al., 1999 ; Kolykhalov et al., 2000).”