The addicted human brain viewed in the light of imaging studies: brain circuits and treatment strategies.

By Nora D. Volkow, J. S. Fowler, Gene-Jack Wang. Neuropharmacology, 2004

628 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Cognitive Neuroscience

View Paper: https://www.semanticscholar.org/paper/df21926a3c20427a88a666a32241774cf481e6cf

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In Cellular and Molecular Neuroscience

In Cognitive Neuroscience

Citations in the corpus

Neural systems of reinforcement for drug addiction: from actions to habits to compulsion (2005, methodology): “Studies using PET, especially, highlight changes in metabolism in the OFC in abstinent drug abuser”
Neurocircuitry of Addiction (2009, background): “The cingulate gyrus is also involved and is a brain region implicated in inhibitory control and conflict resolution, disruption of which results in impulsivity (Volkow et al, 2004b).”
Drug Wanting: Behavioral Sensitization and Relapse to Drug-Seeking Behavior (2011, background): “In addition, imaging research has demonstrated that cues activate both the hippocampus and amygdala in experienced drug users (Grant et al., 1996; Childress et al., 1999; Kilts et al., 2001; Volkow et al., 2004).”
Neural substrates of smoking cue reactivity: A meta-analysis of fMRI studies (2011, neutral): “A fundamental assumption of addiction theory is that cue reactivity should only be observed in addicts (Everitt & Robbins, 2005; Glautier & Tiffany, 1995; Koob & LeMoal, 2001; Robinson & Berridge, 2003; Volkow et al., 2004 ).”
Decision making, impulse control and loss of willpower to resist drugs: a neurocognitive perspective (2005, background): “Early on, abnormalities in the VMPC region were observed in cocaine addict”
Managing Addiction as a Chronic Condition (2007, background): “…substance use is associated with physical changes in the brain that have an impact on brain functioning and emotional states (Chang et al., 2005, 2006; Kufahl et al., 2005; Paulus, Tapert, and Schuckit, 2005; Risinger et al., 2005; Schlaepfer et al., 2006; Volkow, Fowler, and Wang, 2003, 2004).”
Implicit Cognition and Addiction: A Tool for Explaining Paradoxical Behavior (2010, background): “…may result in a fundamental imbalance by increasing the effects of relatively automatic appetitive processes (as witnessed by the stronger implicit cognitive processes in heavy versus light drinkers, for example) and by weakening executive control and motivation to regulate appetitive impulses.”