Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion
By Marta Florio, Mareike Albert, E. Taverna, Takashi Namba, Holger Brandl, E. Lewitus, Christiane Haffner, A. Sykes, F. K. Wong, Jula Peters and 10 more. Science, 2015
602 citations recorded by the source corpus.
Subfields: Molecular Biology
View Paper: https://www.semanticscholar.org/paper/df20184ab380232bb78c8a6fa34b0cc18993f7e6
How researchers see this paper
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In Molecular Biology
- Hongjun Song
- Guo-li Ming
- Xuyu Qian
- Marta Florio
- Juergen A. Knoblich
- Svante Pääbo
- W. Huttner
- Fred H. Gage
Citations in the corpus
- The Cellular and Molecular Landscapes of the Developing Human Central Nervous System (2016, unknown): “In a complementary approach, Florio et al. (2015) used differential labeling of apical (iRG) and basal (oRG) RG cells to sort these two populations for RNA sequencing in mouse and human fetal neocortex.”
- Brain organoids: advances, applications and challenges (2019, background): “…and mechanical forces, have been found to influence the complex but highly controlled process of gyrification during late human corticogenesis (Bae et al., 2014; Bayly et al., 2014; Del Toro et al., 2017; Florio et al., 2015; Nowakowski et al., 2016; Stahl et al., 2013; Zilles et al., 2013).”
- Human cerebral organoids recapitulate gene expression programs of fetal neocortex development (2015, methodology): “We next used all expressed genes to characterize cells based on their maximum correlation with bulk RNA-seq data from laser-dissected germinal zones, namely VZ (containing a majority of aRG), iSVZ and oSVZ (containing a majority of bIPs, bRG neurons, and migrating neurons), and CP (containing mature”
- Molecular Identity of Human Outer Radial Glia During Cortical Development (2015, unknown): “…between microdissected samples (Fietz et al., 2012; Miller et al., 2014) and between cell populations expressing particular surface proteins (Florio et al., 2015; Johnson et al., 2015), but the difficulty of isolating bona fide oRG cells has made clear definition of their gene expression…”