Human Umbilical Cord Perivascular (HUCPV) Cells: A Source of Mesenchymal Progenitors

By R. Sarugaser, D. Lickorish, D. Baksh, M. Hosseini, J. Davies. Stem Cells, 2005

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Isolation and characterization of human umbilical cord mesenchymal stem cells with hematopoiesis-supportive function and other potentials. (2006, neutral): “described that the cells from perivascular umbilical cord could not be induced into neural cells.(18) This discrepancy may be due to the different methods of isolation or culture, by which the different subpopulation of MSC were isolated and expanded in vitro.”
Mesenchymal stromal cells: new directions. (2012, background): “, 2000), umbilical cord perivascular cells (Sarugaser et al., 2005), umbilical cord Wharton’s jelly (Wang et al.”
Different populations and sources of human mesenchymal stem cells (MSC): A comparison of adult and neonatal tissue-derived MSC (2011, background): “MSC) [38-40] or from umbilical cord blood (CB-MSC), [41,42] which also harbors hematopoietic stem cells, endothelial precursor cells and endothelial colony-forming cells (Figure 1).”
Multipotent mesenchymal stromal cells obtained from diverse human tissues share functional properties and gene-expression profile with CD146+ perivascular cells and fibroblasts. (2008, result): “The isolation of MSC from the subendothelium of various arteries and veins, including umbilical vein [36,75,76], saphena vein [39], umbilical artery and fetal carotid (in this article), and bovine aorta [16,17] is in agreement with our hypothesis.”