Voluntary exercise induces a BDNF-mediated mechanism that promotes neuroplasticity.

By F. Gomez-Pinilla, Z. Ying, Roland R. Roy, R. Molteni, V. Reggie Edgerton. Journal of Neurophysiology, 2002

747 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Developmental Neuroscience, Pathology and Forensic Medicine

View Paper: https://www.semanticscholar.org/paper/def4efb5bcfaeaa7de90239963d7b6316ded0bff

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In Cellular and Molecular Neuroscience

In Developmental Neuroscience

Citations in the corpus

The Influence of Exercise on Cognitive Abilities (2013, positive): “For example, exercise influences the production of BDNF in the area vital for learning and memory, the hippocampus (78, 128, 189).”
Harnessing neuroplasticity for clinical applications (2011, positive): “Aerobic exercise is associated with increased neurogenesis and angiogenesis, as well as the production of neurotrophic molecules such as brain-derived neurotrophic factor and other growth factors involved in neuroprotection and the promotion of cell survival, neurite outgrowth and synaptic plasticit”
Ankle dorsiflexion as an fMRI paradigm to assay motor control for walking during rehabilitation (2004, background): “…production of neurotrophins, and other biological responses to motor learning (Biernaskie et al., 2004; Cramer and Chopp, 2000; Frost et al., 2003; Gomez-Pinilla et al., 2002; Johansson and Belichenko, 2002; Kleim et al., 2002; Lotze et al., 2003a; Morgen et al., 2004; Rossini et al., 2003;…”
Exercise is the real polypill. (2013, background): “Increased BDNF transcripts in exercised rodents’ brains are well documented, providing mechanistic support for a beneficial exercise effect in cognitive function (4, 5, 30, 153, 193, 275, 315, 333, 334, 352, 396, 417, 425, 460, 488, 507), e.”
Aerobic Exercise and Neurocognitive Performance: a Meta-Analytic Review of Randomized Controlled Trials (2010, result): “The finding that aerobic exercise improves memory is consistent with several animal studies, which have indicated that physical activity increases brain-derived neurotrophic factor expression (80) in the hippocampus and perihippocampal structures (81,82).”