New stereological methods for counting neurons.

By M. West. 1993

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Citations in the corpus

Human Hippocampal Neurogenesis Persists throughout Aging (2018, neutral): “In each region, we characterized and quantified angiogenesis, volume, and cells at different maturational stages in the DG neurogenic niche, using unbiased stereological methods (West, 1993).”
Neural plasticity in the ageing brain (2006, background): “In the 1980s, when new stereological principles were developed, it became possible to identify and eliminate many of the confounding factors of the previous studies that had indicated a profound decline in neuron number occurring in advanced ag”
Environment-specific expression of the immediate-early gene Arc in hippocampal neuronal ensembles (1999, background): “This approach, which is essentially an optical dissector techniqu”
The Search for True Numbers of Neurons and Glial Cells in the Human Brain: A Review of 150 Years of Cell Counting (2016, background): “Several studies have documented the surprisingly wide range of neurons in human cerebral cortex between individuals (biological variance, Haug, 1986, 1987; Terry et al., 1987; West, 1993a).”
Design-based stereology in neuroscience. (2005, background): “…Lekan (1996), Mayhew and Gundersen (1996) and Royet (1991) provide introductions to the basic concepts of quantification, probes and sampling, whereas the papers by Gundersen et al. (1988), Mayhew (1992), Hyman et al. (1998) and particularly West (1993, 1999, 2002) are more application oriented.”
Genetic or pharmacological iron chelation prevents MPTP-induced neurotoxicity in vivo: a novel therapy for Parkinson's disease. (2003, unknown): “Neuronal counts were performed on TH -positive SN neurons using the unbiased dissector method (West, 1993).”
Postmortem studies in mood disorders indicate altered numbers of neurons and glial cells. (2000, background): “For the estimation of total number of neurons or glia in a particular brain region, it is essential that the borders of this region be established so that sampling is confined to the region within these borders (Gundersen et al 1988; West 1993).”
Peripheral Infusion of IGF-I Selectively Induces Neurogenesis in the Adult Rat Hippocampus (2000, background): “…two cell diameters below the GCL, ignoring the cells in the uppermost focal plane and focusing through the thickness of the section to avoid errors caused by oversampling [for a discussion of the optical dissector principle, see Gundersen et al. (1988); West (1993); Coggeshall and Lekan (1996)].”
Adult neurogenesis produces a large pool of new granule cells in the dentate gyrus (2001, methodology): “…cells were counted at 4003 (Olympus BH-2) in the granule cell layer (defined as any cell touching other cells in the layer) and hilus on every 12th section through the entire dentate gyrus, according to a modified version of the fractionator method (Guillery and Herrup, 1997; West, 1993).”