Review - Part of the Special Issue: Alzheimer's Disease - Amyloid, Tau and Beyond Alzheimer disease: Epidemiology, diagnostic criteria, risk factors and biomarkers

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Clearance systems in the brain—implications for Alzheimer disease (2015, background): “(1) CSF influx, unidirectionally with blood flow, into the periarterial space (between the basement membrane of smooth”
A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease. (2017, unknown): “AD typically progresses in three general stages; earlystage, mild-moderate, and severe (Reitz and Mayeux, 2014).”
Brain-Gut-Microbiota Axis in Alzheimer’s Disease (2019, background): “Those genes code proteins which are involved in amyloid precursor protein (APP) metabolism, immune response, inflammation, intracellular trafficking, or lipid metabolism, indicating the potential pathogenetic factors.(8) Other, non-genetic, risk factors for LOAD encompass”
Role of pro-inflammatory cytokines released from microglia in Alzheimer's disease. (2015, background): “Alzheimer’s disease (AD) is a chronic, multifactorial neurodegenerative disorder in people over the age of 65 (1), which creates a huge burden to affected individuals, their families, and society (2).”