Eicosanoid storm in infection and inflammation

By Edward A. Dennis, Paul C. Norris. Nature reviews. Immunology, 2015

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Omega-3 and omega-6 polyunsaturated fatty acids: Dietary sources, metabolism, and significance - A review. (2018, background): “Diets enriched in n-6 PUFAs are associated with inflammation, constriction of blood vessels, and platelet aggregation [2].”
Strengthening the Immune System and Reducing Inflammation and Oxidative Stress through Diet and Nutrition: Considerations during the COVID-19 Crisis (2020, background): “Eicosanoid signaling resembles that of cytokine signaling and is part of the innate immune response [133].”
PEBP1 Wardens Ferroptosis by Enabling Lipoxygenase Generation of Lipid Death Signals (2017, background): “As PUFA-PLs make up the most abundant structural membrane components, oxygenation of AA-PE requires a highly selective mechanism.”
Role of neuroinflammation in neurodegeneration development (2023, background): “Resolution is a highly coordinated process that occurs in response to inflammation to limit tissue damage and promote repair.(418) It is widely accepted that resolution processes are initiated early during inflammation.”