When cilia go bad: cilia defects and ciliopathies

By M. Fliegauf, T. Benzing, H. Omran. Nature reviews. Molecular cell biology, 2008

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The conserved Bardet-Biedl Syndrome proteins assemble a coat that traffics membrane proteins to cilia (2010, positive): “…olfaction, planar cell polarity, and Hedgehog signaling and since the receptor for each of these signaling pathways has been localized to the primary cilium (Fliegauf et al., 2007), the targeting of signaling receptors to cilia is thought to be crucial for signal sensing and transduction.”
Photoreceptor degeneration: genetic and mechanistic dissection of a complex trait (2010, neutral): “Many ciliary proteins are also expressed in other cellular compartments and in non-ocular cells, which accounts for the non-ocular features of many ciliopathies that include R”
Post-translational regulation of the microtubule cytoskeleton: mechanisms and functions (2011, background): “The prime candidates for such diseases are those previously connected to malfunctions of those microtubules that normally exhibit high levels of PTMs, such as ciliopathies”
Cilia and Mucociliary Clearance (2017, background): “eated the physiological role that motile cilia play elsewhere in the body (Fliegauf et al. 2007).”