Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation

By L. Jackson‐Grusby, C. Beard, Richard L. Possemato, M. Tudor, D. Fambrough, G. Csankovszki, J. Dausman, Peggy P. Lee, Christopher B Wilson, Eric S. Lander and 1 more. Nature Genetics, 2001

742 citations recorded by the source corpus.

Subfields: Genetics, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/dc4570aaa8057c6bcc8aa7e1a3a8e182efe22a51

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Genetics

1. Alexander Meissner
2. R. Klose
3. P. Molloy
4. B. Power
5. Ann Wilson
6. Shireen A. Sarraf
7. I. Stancheva
8. Suzanne M. McDermott

In Molecular Biology

1. Alexander Meissner
2. K. Hochedlinger
3. Bradley E. Bernstein
4. M. Stadtfeld
5. A. Bird
6. Eric S. Lander
7. R. Klose
8. P. Molloy

Citations in the corpus

• DNA hypomethylation and human diseases. (2007, background): “Levels of DNMT1 have been studied in a range of tumor types—where changes in expression levels correlate with cellular proliferative rate [143,144].”
• Induced pluripotency: history, mechanisms, and applications. (2010, background): “Otherwise, cell death pathways such as the p53 pathway would have to be inactivated to ensure survival of cells (Jackson-Grusby et al. 2001).”
• DNA Methylation and Its Basic Function (2013, background): “However, in vitro differentiation results in massive cell death, recapitulating the phenotype observed in knockout embryos (Jackson-Grusby et al, 2001).”