Abstract 5606: Detection of circulating tumor DNA in early and late stage human malignancies

By C. Bettegowda, M. Sausen, R. Leary, I. Kinde, N. Agrawal, Bjarne R. Bartlett, Brandon S. Luber, Kenneth W. Kinzler, Bert Vogelstein, N. Papadopoulos and 1 more. 2014

4,314 citations recorded by the source corpus.

Subfields: Cancer Research, Oncology, Pathology and Forensic Medicine

View Paper: https://www.semanticscholar.org/paper/dc3f7dd2ffd424d580de5ef7715ea5b02fbd7e55

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cancer Research

1. Nicholas McGranahan
2. K. Pantel
3. Charles Swanton
4. J. Reis-Filho
5. D. Hoon
6. Jay Shendure
7. Raghu Kalluri
8. C. Alix‐Panabières

In Oncology

1. Nicholas McGranahan
2. J. Reis-Filho
3. Charles Swanton
4. Raghu Kalluri
5. K. Pantel
6. R. Weinberg
7. C. Alix‐Panabières
8. D. Hanahan

In Pathology and Forensic Medicine

1. J. Reis-Filho
2. K. Pantel

Citations in the corpus

• Liquid biopsy: a step closer to transform diagnosis, prognosis and future of cancer treatments (2022, positive): “Digital PCR has been shown to detect ctDNA in more than 75% of patients with advanced CRC, BC, and PC and to a good extent in patients with localized tumors [38, 100].”
• Clonal Heterogeneity and Tumor Evolution: Past, Present, and the Future. (2017, positive): “Likewise, following EGFR monoclonal antibody therapy, multiple KRAS mutations have been observed in circulating free DNA (Bettegowda et al., 2014; Misale et al., 2012).”
• Systems Biology of Cancer Metastasis (2019, positive): “The development of less invasive tests, such as liquid biopsies for cancer biomarkers(Bettegowda et al., 2014) has opened an avenue for the wider application of precision medicine for pre-emptive surveillance for cancer initiation, metastatic growth(Li et al., 2010), chances of metastasis after…”