Microfluidic platform for controlled synthesis of polymeric nanoparticles.

By R. Karnik, F. Gu, P. Basto, C. Cannizzaro, L. Dean, William Kyei-Manu, Robert Langer, O. Farokhzad. Nano letters (Print), 2008

827 citations recorded by the source corpus.

Subfields: Biomedical Engineering

View Paper: https://www.semanticscholar.org/paper/3034e28dfb5fd588bac00c631b91ffe95d7fce36

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In Biomedical Engineering

Citations in the corpus

Advanced Materials and Processing for Drug Delivery: The Past and the Future (2012, background): “The NPs or microparticles generated from microfluidics platform typically have a narrower size distribution than those acquired by conventional methods [146, 157].”
Cancer nanotechnology: the impact of passive and active targeting in the era of modern cancer biology. (2014, background): “The optimisation of NPs’ efficacy therefore also involves optimal drug release rates whether through controlled diffusional release [135], covalent conjugation of the drug to a polymer backbone [136, 137] or environment-triggered release [138, 139].”
Nanoparticle synthesis in microreactors (2011, methodology): “nanoprecipitation (Karnik et al., 2008).”
Microfluidic Devices for Drug Delivery Systems and Drug Screening (2018, background): “Increasing the flow ratio, R, in a fixed geometry can enhance the production rate and increase the average diameter of synthesized nanoparticles [27,30,31].”
PEGylation as a strategy for improving nanoparticle-based drug and gene delivery (2015, neutral): “than fully partitioning to the NP surface [201].”
Small particles, big impacts: A review of the diverse applications of nanofluids (2013, background): “[148–150] Polymer Nanoparticles Biomedical (Drug delivery), Conductive Optioelectronics”
Control of Polymeric Nanoparticle Size to Improve Therapeutic Delivery (2015, background): “For instance, the Karnik and Farokhzad groups have developed several microfluidic platforms capable of generating size-tunable polyethylene glycol-b-poly(lacticco-glycolic acid) (PEG-b-PLGA) NPs with narrower size distribution, higher drug loading capacity, and improved batch-to-batch consistency wh”
Porous Polymer Particles - A Comprehensive Guide to Synthesis, Characterization, Functionalization and Applications (2012, methodology): “[278-280] and electrical sensing zone (also called Coulter counter) [45, 281-282] are rather sensitive instrument-based methods to determine size and size distribution.”