Dopamine in germinal centers

By I. Vişan. Nature Immunology, 2017

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B-Cell Epitope Mapping of TprC and TprD Variants of Treponema pallidum Subspecies Informs Vaccine Development for Human Treponematoses (2022, background): “Upon immunization, the immunodominance hierarchy is established at the germinal center, where B cells compete for the antigen through based on binding affinity, and subsequently undergo clonal expansion to become plasma cells or memory B cells (56).”
T follicular helper cell biology: A decade of discovery and diseases (2019, background): “Tfh cells are important for GC, Ab, and long-lived PC responses to protein immunizations, including the process of affinity maturation (Crotty, 2014; Victora and Nussenzweig, 2012).”