Oriented endocytic recycling of α5β1 in motile neutrophils

By L. Pierini, M. Lawson, R. Eddy, B. Hendey, F. Maxfield. 2000

142 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Force Measurements of the α5β1 Integrin–Fibronectin Interaction (2003, background): “The interaction between a5b1 integrin and fibronectin (FN) plays an important role in cell differentiation, proliferation (Garcia et al., 1999; Molla and Block 2000) and migration ( Pierini et al., 2000 ) by serving as a bridge between the cell and the extracellular matrix that mediates bidirectiona”
Complexes of tetraspanins with integrins: more than meets the eye. (2001, background): “It is currently recognised that targeted delivery of integrins to the leading edge of migrating cells and their recycling may help to perpetuate lamellipodial extensions (Fabbri et al., 1999; Lauffenburger and Horwitz, 1996; Pierini et al., 2000).”
Dynamic Partitioning into Lipid Rafts Controls the Endo-Exocytic Cycle of the αL/β2 Integrin, LFA-1, during Leukocyte Chemotaxis (2005, methodology): “Additional evidence shows that integrin-containing vesicles move from the perinuclear region to the base of the lamellipodium in fibroblasts, and to an endosomal recycling compartment near the cell front in neutrophils ( Pierini et al., 2000, 2003 ).”