Force Measurements of the α5β1 Integrin–Fibronectin Interaction

By Feiya Li, S. Redick, H. Erickson, V. Moy. 2003

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Molecular Basis for the Dynamic Strength of the Integrin α4β1/VCAM-1 Interaction (2004, background): “The high-affinity form of a4b1 was induced by activation antibody TS2/16, bypassing the requirements of inside-out signal from the cells (Alon et al., 1995; Chen et al., 1999; Li et al., 2003).”
Atomic force microscopy as a multifunctional molecular toolbox in nanobiotechnology. (2008, background): “and for biotechnologists addressing cell adhesion to biofunctionalized surface”
Detection and localization of single molecular recognition events using atomic force microscopy (2006, background): “Strategies for creating cell-probes involve the use of specific receptor-ligand interaction”
Revealing Early Steps of α2β1 Integrin-mediated Adhesion to Collagen Type I by Using Single-Cell Force Spectroscopy (2007, background): “Several SCFS studies showed that rupturing integrin–ligand bonds requires overcoming at least two activation energy barriers (Zhang et al., 2002; Li et al., 2003).”
Demonstration of catch bonds between an integrin and its ligand (2009, neutral): “However, published work did not observe integrin– ligand catch bonds (Zhang et al., 2002, 2004; Li et al., 2003).”