Chitosan: An Update on Potential Biomedical and Pharmaceutical Applications
By R. Cheung, T. Ng, J. Wong, W. Chan. Marine Drugs, 2015
1,105 citations recorded by the source corpus.
Chitosan is a natural polycationic linear polysaccharide derived from chitin. The low solubility of chitosan in neutral and alkaline solution limits its application. Nevertheless, chemical modification into composites or hydrogels brings to it new functional properties for different applications. Chitosans are recognized as versatile biomaterials because of their non-toxicity, low allergenicity, biocompatibility and biodegradability. This review presents the recent research, trends and prospects in chitosan. Some special pharmaceutical and biomedical applications are also highlighted.
Subfields: Biomaterials, Pharmaceutical Science
View Paper: https://www.semanticscholar.org/paper/d9d0a1ee459d26b482d63e7a73958875df846b18
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Citations in the corpus
- Chitosan as a Wound Dressing Starting Material: Antimicrobial Properties and Mode of Action (2019, background): “Moreover, chitosan may form a dense film on the cell surface, which may interfere with fungal growth and activate several defense mechanisms such as chitinase accumulation, callus synthesis, and proteinase inhibitor synthesis and lignification [43].”
- Preparation and In Vitro Characterization of Chitosan Nanoparticles and Their Broad-Spectrum Antifungal Action Compared to Antibacterial Activities against Phytopathogens of Tomato (2019, background): “Cationic properties of CS rather than CNPs induce positively charged quaternary groups to hydroxyl or amino groups that are primarily responsible for antibacterial activities [34].”
- Antimicrobial Actions and Applications of Chitosan (2021, background): “Furthermore, chitosan with a high DDA has been shown to exhibit a more positive charge than chitosan with a low DDA in the same acidic environment [68,90,103,107,121,122,170,171].”