Antibiotic resistance among gram-negative bacilli in US intensive care units: implications for fluoroquinolone use.

By M. Neuhauser, Robert A. Weinstein, R. Rydman, L. Danziger, G. Karam, J. Quinn. Journal of the American Medical Association (JAMA), 2003

714 citations recorded by the source corpus.

Subfields: Applied Microbiology and Biotechnology, Critical Care and Intensive Care Medicine, Molecular Medicine

View Paper: https://www.semanticscholar.org/paper/d9c960df348fc6d48cadd07c504bad92f1c88b6f

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Applied Microbiology and Biotechnology

1. K. Bush
2. S. Cosgrove
3. 古谷 良輔
4. 山口 和将
5. P. Tamma
6. L. Maragakis
7. G. Jacoby
8. P. Bradford

In Critical Care and Intensive Care Medicine

1. Emily R. M. Sydnor
2. S. Cosgrove
3. 古谷 良輔
4. 山口 和将
5. Trish Perl
6. Theodore J. Iwashyna
7. P. Tamma
8. J. Bartlett

In Molecular Medicine

1. D. Hooper
2. Ari Robicsek
3. G. Jacoby
4. K. Bush
5. J. Strahilevitz
6. S. Cosgrove
7. 古谷 良輔
8. 山口 和将

Citations in the corpus

• Fluoroquinolone-modifying enzyme: a new adaptation of a common aminoglycoside acetyltransferase (2006, background): “The advantage to the bacterium conferred by such a gene in the presence of either fluoroquinolones or aminoglycosides may have a role in the frequently observed but incompletely understood strong epidemiologic association between ciprofloxacin and aminoglycoside resistanc”
• Bad bugs, no drugs: no ESKAPE! An update from the Infectious Diseases Society of America. (2009, background): “Aminoglycoside resistance is emerging as a significant problem [4, 81, 82].”
• The Timing of Early Antibiotics and Hospital Mortality in Sepsis (2017, background): “Unnecessary antibiotics can result in adverse patient-specific and communitylevel consequences (11, 12).”
• Combination Therapy for Treatment of Infections with Gram-Negative Bacteria (2012, background): “The available evidence shows that the proportion of Gram-negative organisms resistant to commonly used antibiotics is increasing (97, 184, 192, 202).”
• 2007 Guideline for Isolation Precautions: Preventing Transmission of Infectious Agents in Health Care Settings (2007, methodology): “The absence of standardized screening media for many gramnegative bacilli can make the process of isolating a specific MDR-GNB a relatively labor-intensive process.(38,190,241,250) n Rapid detection methods: Using conventional culture methods for active surveillance can result in a delay of 2 to 3 d”
• Antibiotic resistance and extended spectrum beta-lactamases: Types, epidemiology and treatment. (2015, background): “PER-1 was first detected in P. aeruginosa (Neuhauser et al., 2003), and later in S. enterica serovar Typhimurium and Acinetobacter isolates as well (Vahaboglu et al., 2001).”
• Hospital Epidemiology and Infection Control in Acute-Care Settings (2011, background): “In one hospital, susceptibility to ciprofloxacin, an agent with broad Gram-negative coverage, fell from 86% to 76% over 5 years (230).”
• Mechanisms of resistance to quinolones. (2005, background): “In the 1990s, the use of fluoroquinolones in the United States increased by ~40%, with a doubling in the rate of resistance to ciprofloxacin among gram-negative bacilli isolated from the intensive care units of hospitals [1].”
• Guidelines for the management of adults with hospital-acquired, ventilator-associated, and healthcare-associated pneumonia. (2008, background): “aeruginosa sensitivity to quinolones resulted with widespread use of these agents in hospital (264, 265).”