Survival of Staphylococcus aureus Inside Neutrophils Contributes to Infection1

By H. Gresham, J. Lowrance, T. Caver, B. Wilson, A. Cheung, F. Lindberg. 2000

499 citations recorded by the source corpus.

Subfields: Immunology, Infectious Diseases

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Immunology

1. Victor J. Torres
2. Francis Alonzo
3. Tamara Reyes-Robles
4. W. Nauseef
5. C. Winterbourn

In Infectious Diseases

1. Victor J. Torres
2. Francis Alonzo
3. Tamara Reyes-Robles
4. Ashley L. DuMont
5. Bo Shopsin
6. F. DeLeo
7. M. Otto

Citations in the corpus

• Intracellular staphylococcus aureus: Live-in and let die (2012, unknown): “What is the nature of tight and spacious vacuoles (Gresham et al., 2000) that are occupied by, for example, sarA− and sarA+ S. aureus, respectively?”
• Acute Septic Arthritis (2002, background): “aureus was found within polymorphonuclear neutrophils in an in vivo infection model, and these infected host cells were able to establish infection in naı̈ve animals (65).”
• Phagocytosis of Staphylococcus aureus by human neutrophils prevents macrophage efferocytosis and induces programmed necrosis (2014, background): “(29) reported that deficiency in CD47 results in less bacterial burden and increased survival of mice i.”
• Characterization of a new cytotoxin that contributes to Staphylococcus aureus pathogenesis (2010, background): “…infection is the formation of abscesses (Ogston, 1882), a battle ground where S. aureus combats leukocytes, the primary and most important line of defence against S. aureus infection (Verdrengh and Tarkowski, 1997; Gresham et al., 2000; LekstromHimes and Gallin, 2000; Corbin et al., 2008).”
• Identification and treatment of the Staphylococcus aureus reservoir in vivo (2016, unknown): “Studies dating back over half a century have shown that S. aureus can survive in vitro in endothelial cells, epithelial cells, osteoclasts, and even in professional phagocytes such as neutrophils and macrophages (Rogers, 1956; Gresham et al., 2000; Koziel et al., 2009; Tuchscherr et al., 2011).”
• Staphylococcus aureus leukotoxin ED targets the chemokine receptors CXCR1 and CXCR2 to kill leukocytes and promote infection. (2013, background): “It is however well established that antibody-mediated depletion of PMNs in systemic models of infection renders mice hyper-susceptible to S. aureus-mediated death (Alonzo et al., 2012; Corbin et al., 2008; Gresham et al., 2000).”