CSF-1 receptor signaling in myeloid cells.

By E. Stanley, V. Chitu. Cold Spring Harbor Perspectives in Biology, 2014

729 citations recorded by the source corpus.

Subfields: Immunology, Oncology

View Paper: https://www.semanticscholar.org/paper/5f830d624a2707131a3c6994a73427570e8ba13e

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Immunology

1. D. Holtzman
2. M. Colonna
3. M. Cella
4. Shizuo Akira

In Oncology

1. M. Colonna
2. D. Holtzman

Citations in the corpus

• TREM2 lipid sensing sustains microglia response in an Alzheimer’s disease model (2015, positive): “Since CSF-1R captures CSF-1 and targets it for degradation (Stanley and Chitu, 2014), the reduced survival of Trem2−/− microglia at low CSF-1 concentrations may reflect a marked susceptibility of these cells to CSF-1 deprivation that occurs when microglia consume a limited supply of CSF-1.”
• Colony-stimulating factor 1 receptor (CSF1R) inhibitors in cancer therapy (2017, background): “CSF1 receptor (CSF1R)-mediated signaling is crucial for the differentiation and survival of the mononuclear phagocyte system and macrophages in particular [7].”