Impaired Nitric Oxide Synthase Pathway in Diabetes Mellitus: Role of Asymmetric Dimethylarginine and Dimethylarginine Dimethylaminohydrolase

By Ken Y. Lin, Akira Ito, T. Asagami, P. Tsao, S. Adimoolam, M. Kimoto, H. Tsuji, G. Reaven, J. Cooke. Circulation, 2002

715 citations recorded by the source corpus.

Subfields: Cardiology and Cardiovascular Medicine, Molecular Biology, Physiology

View Paper: https://www.semanticscholar.org/paper/d78b405b000830489797bab77a25ea5a481a0cff

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cardiology and Cardiovascular Medicine

1. U. Förstermann
2. M. Félétou

In Molecular Biology

1. U. Förstermann
2. W. Sessa

In Physiology

1. U. Förstermann
2. M. Félétou

Citations in the corpus

• Endothelial dysfunction and vascular disease – a 30th anniversary update (2017, background): “In both hypertensive animals and humans, the reduced NO bioavailability in response to endothelium-dependent stimuli has been attributed to higher circulating levels of ADMA (Perticone et al. 2005, Sasser et al. 2014).”
• Nitric oxide synthases: regulation and function. (2012, background): “129 The activities (not the expression) of the key enzyme for ADMA production, protein arginine N -methyltransferase (PRMT, type I), 130 and of the ADMA-degrading enzyme dimethylarginine dimethylaminohy-drolase (DDAH) 131 are redox-sensitive.”