Pseudomonas aeruginosa and other predictors of mortality and morbidity in young children with cystic fibrosis

By J. Emerson, M. Rosenfeld, S. Mcnamara, B. Ramsey, R. Gibson. Pediatric Pulmonology, 2002

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Pseudomonas aeruginosa: resistance and therapeutic options at the turn of the new millennium. (2007, background): “The definition of chronic colonisation is still a matter of debate [138,139], but there is no doubt that this state has a major negative impact on the patient’s prognosis, as it is associated with an accelerated decline of respiratory function (forced expiratory volume in 1 s (FEV1)) [140–142], shor”
Cystic fibrosis pulmonary guidelines: chronic medications for maintenance of lung health. (2007, neutral): “Because chronic colonization of the airways with this bacterium is associated with a more rapid decline in lung function (5), aerosolized antibiotics have been advocated both for eradication of initial infection and for suppression of the chronic infection.”
The Epidemiology, Pathogenesis and Treatment of Pseudomonas aeruginosa Infections (2012, background): “aeruginosa.[41] Even Of additional concern is the frequent isolation of after lung transplantation, P.”
Pathophysiology and management of pulmonary infections in cystic fibrosis. (2003, background): “cepacia (142, 143) and frequency of pulmonary exacerbations (122).”