Altered circadian rhythms regulate growth vigor in hybrids and allopolyploids
By Z. Ni, Eun-Deok Kim, M. Ha, Erika Lackey, Jianxin Liu, Yirong Zhang, Qixin Sun, Z. Chen. Nature, 2008
665 citations recorded by the source corpus.
Segregating hybrids and stable allopolyploids display morphological vigour, and Arabidopsis allotetraploids are larger than the parents Arabidopsis thaliana and Arabidopsis arenosa—the mechanisms for this are unknown. Circadian clocks mediate metabolic pathways and increase fitness in animals and plants. Here we report that epigenetic modifications of the circadian clock genes CIRCADIAN CLOCK ASSOCIATED 1 (CCA1) and LATE ELONGATED HYPOCOTYL (LHY) and their reciprocal regulators TIMING OF CAB EXPRESSION 1 (TOC1) and GIGANTEA (GI) mediate expression changes in downstream genes and pathways. During the day, epigenetic repression of CCA1 and LHY induced the expression of TOC1, GI and downstream genes containing evening elements in chlorophyll and starch metabolic pathways in allotetraploids and F1 hybrids, which produced more chlorophyll and starch than the parents in the same environment. Mutations in cca1 and cca1 lhy and the daily repression of cca1 by RNA interference (RNAi) in TOC1::cca1(RNAi) transgenic plants increased the expression of downstream genes and increased chlorophyll and starch content, whereas constitutively expressing CCA1 or ectopically expressing TOC1::CCA1 had the opposite effect. The causal effects of CCA1 on output traits suggest that hybrids and allopolyploids gain advantages from the control of circadian-mediated physiological and metabolic pathways, leading to growth vigour and increased biomass.
Subfields: Molecular Biology, Plant Science
View Paper: https://www.semanticscholar.org/paper/d692163d5927196898465b0a02bd8dba671e99cc
How researchers see this paper
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In Molecular Biology
- Alison M. Smith
- Mark Stitt
- J. Doyle
- Z. J. Chen
- Jeremy E. Coate
- P. K. Endress
- Henrik Hartmann
- Susan Trumbore
In Plant Science
- Alison M. Smith
- Mark Stitt
- Michael J. O. Pocock
- J. Doyle
- W. Kunin
- Z. J. Chen
- Jeremy E. Coate
- Henrik Hartmann
Citations in the corpus
- Polyploidy, the Nucleotype, and Novelty: The Impact of Genome Doubling on the Biology of the Cell (2019, background): “Since one-third of the Arabidopsis genome is under circadian control (Covington et al. 2008) and allopolyploidy is known to affect circadian behavior in Arabidopsis (Ni et al. 2009), such chromatin modifications could play a role in differences between diploids and autopolyploids.”
- Molecular mechanisms of polyploidy and hybrid vigor (2010, background): “Analyzing genome-wide nonadditively expressed genes in Arabidopsis allotetraploids [82], the authors [101] found that among ∼130 genes upregulated in the allotetraploids, two thirds of them in their upstream regions contain at least one (CCA1)-binding site (CBS; AAAAATCT) or evening element (AAAATAT”
- Circadian control of carbohydrate availability for growth in Arabidopsis plants at night (2010, background): “Although the potential importance for plant productivity of circadian control of carbohydrate metabolism has been recognized previously (6, 7), these studies proposed that the target for circadian control was carbohydrate accumulation in the light, rather than its utilization at night.”
- Ploidy influences rarity and invasiveness in plants (2011, background): “…Guo & Yin 2010) and experimental studies on Phlox drummondii, Solidago gigantea andArabidopsis spp. (Vyas et al. 2007; HullSanders et al. 2009; Ni et al. 2009) have shown that polyploids have a distinct advantage in photosynthetic efficiency, growth, reduced generation time, vigour and…”