SOS response promotes horizontal dissemination of antibiotic resistance genes

By John W. Beaber, B. Hochhut, M. Waldor. Nature, 2004

1,153 citations recorded by the source corpus.

Subfields: Endocrinology, Food Science, Molecular Medicine

View Paper: https://www.semanticscholar.org/paper/d60023231fd10054a4a1a387b6bdaffd435ab1b3

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Citations in the corpus

Morphological plasticity as a bacterial survival strategy (2008, background): “Furthermore, the induction of the SOS response can augment the horizontal transfer of DNA, particularly antibiotic-resistance determinants, among pathogenic bacteri”
Acinetobacter baumannii: Emergence of a Successful Pathogen (2008, background): “More broadly, deepening our understanding of the mechanisms of antimicrobial resistance gene transfer and the cellular responses (such as the SOS response) that lead to mutagenesis and eventual resistance (23, 92, 313) will provide unique targets that, when inhibited, may prevent the emergence and d”
Antimicrobial use in aquaculture re-examined: its relevance to antimicrobial resistance and to animal and human health. (2013, background): “…lysis, as well as that mediated by plasmids in the aquatic environment and in the intestines of fish and terrestrial animals (Stewart and Sinigalliano, 1990; Beaber et al., 2004; Frost et al., 2005; Aarestrup et al., 2008; Allen et al., 2011; Domingues et al., 2012; Looft et al., 2012).”
Review of Antimicrobial Resistance in the Environment and Its Relevance to Environmental Regulators (2016, background): “The SOS response can also trigger HGT of ARGs, thereby providing a mechanism for the spread of ARGs from exposure to antibiotics (Beaber et al., 2004).”
A Brief History of the Antibiotic Era: Lessons Learned and Challenges for the Future (2010, background): “, 2010b)? What is the impact of the environmental stresses, such as, for example, the SOS response-inducing UV radiation, on the horizontal dissemination of antibiotic resistance genes (Beaber et al., 2004)? What is the rate of decay of the released antibiotic resistance genes in the environment, gi”
Biofilm-Related Infections: Bridging the Gap between Clinical Management and Fundamental Aspects of Recalcitrance toward Antibiotics (2014, background): “SOS induction may promote mobilization of various mobile elements, such as integrating conjugative elements (177).”
Antibiotics and the gut microbiota. (2014, positive): “DNA synthesis–inhibiting antibiotics have been shown to induce interspecies exchange of integrating conjugative elements encoding multidrug resistance (57).”
Antibiotic-Induced Changes in the Intestinal Microbiota and Disease. (2016, background): “cholerae isolates from patients, potentially a result of antibiotic-induced resistance transfer [113].”
Integrative and conjugative elements: mosaic mobile genetic elements enabling dynamic lateral gene flow (2010, background): “As SetR is similar to phage λ CI, the SetR-mediated repression of transfer genes may be relieved by recombinase A ( RecA )-assisted autocleavage of Set”