Cortical activation and synchronization during sentence comprehension in high-functioning autism: evidence of underconnectivity.

By Marcel Adam Just, V. Cherkassky, T. Keller, Nancy J. Minshew. Brain : a journal of neurology, 2004

1,610 citations recorded by the source corpus.

Subfields: Cognitive Neuroscience, Psychiatry and Mental health

View Paper: https://www.semanticscholar.org/paper/d5825064205794faa177f8a8834d8b4214c28448

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Citations in the corpus

Enhanced Perceptual Functioning in Autism: An Update, and Eight Principles of Autistic Perception (2006, background): “…in Just et al., 2004) of significant diminished synchrony of activation among brain regions that were involved in a task, and there is some current latitude between a generalized (Just et al., 2004) vs. a localized (Koshino et al., 2005) interpretation of the broad concept of underconnectivity.”
Why the frontal cortex in autism might be talking only to itself: local over-connectivity but long-distance disconnection. (2005, background): “Since then, there has been disagreement as to whether autism is a disorder of neural underconnectivity [35], overconnectivity [37] or both, in which local connectivity is abnormally increased whereas longdistance connectivity is reduced or abnormally patterned [22,33,38,39].”
A Typical Participation of Visual Cortex during Word Processing in Autism: An fMRI Study of Semantic Decision. (2007, methodology): “The areas of activation found in extrastriate visual cortex correspond to activations seen for mental imagery (Just et al., 2004a;Mellet et al., 2000), even when exclusively auditory stimuli were used as prompts for visual imagery (Just et al., 2004b;Lambert et al., 2004).”
Diffusion tensor imaging of the corpus callosum in Autism (2007, positive): “Interhemispheric functional underconnectivity has been suggested by several recent fMRI studies of autism in language processing and working memory (Just et al., 2004; Koshino et al., 2005, respectively).”
Salience Network–Based Classification and Prediction of Symptom Severity in Children With Autism (2013, positive): “One prevailing theory posits that autism is caused by underfunctioning integrative circuitry, resulting in information integration deficits at the neural and cognitive levels.(6) The underconnectivity theory is based largely on analysis of task-related changes in interregional connectivity during ta”
Neurophysiological and Computational Principles of Cortical Rhythms in Cognition (2010, neutral): “tence comprehension (485), and in the prefronto-parietal”
Common circuit defect of excitatory-inhibitory balance in mouse models of autism (2009, positive): “Clinical studies suggest that decreased inhibitory input and connectivity lead to altered synchronicity between different brain regions, which may be a key contributing factor to the features of ASD [35, 64, 74 – 76].”
Absence of CNTNAP2 leads to epilepsy, neuronal migration abnormalities and core autism-related deficits (2011, positive): “A number of functional neuroimaging studies have reported reduced connectivity in ASD (Just et al., 2004; Villalobos et al., 2005; Cherkassky et al., 2006; Damarla et al., 2010), supporting the notion that the deficits in cognition and behavior associated with ASD are most likely the result of a…”
Accelerated maturation of white matter in young children with autism: A high b value DWI study (2007, background): “Such processes involve intrahemispheric as well as interhemispheric transfer of information which has been found to be abnormal in autism (Just et al., 2004; Minshew et al., 1997).”
Reduced functional connectivity between V1 and inferior frontal cortex associated with visuomotor performance in autism (2005, background): “In a recent study on sentence comprehension in autism, Just et al. (2004) proposed an underconnectivity hypothesis for autism.”
Mapping early brain development in autism. (2007, neutral): “…from that, many have speculated that there might be reduced long-distanceanatomicalconnectivityaswell(Castellietal., 2002; Cherkassky et al., 2006; Just et al., 2004, 2007; Kana et al., 2006; Koshino et al., 2007; Mason et al., 2007; Murias et al., 2007; Rippon et al., 2007; Villalobos et al.,…”
Abnormal functional connectivity of default mode sub-networks in autism spectrum disorder patients (2010, background): “It has been suggested that functional underconnectivity among brain regions might explain ASD symptoms (Just et al., 2004).”