The stunting syndrome in developing countries
By A. Prendergast, J. Humphrey. Paediatrics and International Child Health, 2014
1,079 citations recorded by the source corpus.
Abstract Linear growth failure is the most common form of undernutrition globally. With an estimated 165 million children below 5 years of age affected, stunting has been identified as a major public health priority, and there are ambitious targets to reduce the prevalence of stunting by 40% between 2010 and 2025. We view this condition as a ‘stunting syndrome’ in which multiple pathological changes marked by linear growth retardation in early life are associated with increased morbidity and mortality, reduced physical, neurodevelopmental and economic capacity and an elevated risk of metabolic disease into adulthood. Stunting is a cyclical process because women who were themselves stunted in childhood tend to have stunted offspring, creating an intergenerational cycle of poverty and reduced human capital that is difficult to break. In this review, the mechanisms underlying linear growth failure at different ages are described, the short-, medium- and long-term consequences of stunting are discussed, and the evidence for windows of opportunity during the life cycle to target interventions at the stunting syndrome are evaluated.
Subfields: Nutrition and Dietetics, Pediatrics, Perinatology and Child Health, Psychiatry and Mental health
View Paper: https://www.semanticscholar.org/paper/d566799354802800915b422924f966efa8eca1b1
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Citations in the corpus
- The Human Microbiome and Child Growth - First 1000 Days and Beyond. (2019, background): “Concurrently, the period from introduction of complementary foods (6 months of age) to 2 years of age represents a crucial period for child growth, particularly linear growth [55].”
- Immune Dysfunction as a Cause and Consequence of Malnutrition (2016, background): “How the perinatal immune epigenome affects long-term immune function has not been assessed; however, the heritable impact of malnutrition suggests that the optimal timing for therapeutic interventions to rescue infant growth and development may need to be re-evaluated [20,29].”