Controlled functionalization of the polysaccharide chitin

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Natural origin biodegradable systems in tissue engineering and regenerative medicine: present status and some moving trends (2007, background): “Chitin can be converted into soluble derivatives such as chitosan, carboxymethyl chitin and glycochitin, among others (Kurita 2001).”
Chemically modified chitin and chitosan as biomaterials (2004, background): “Most studies have been published in reviews and books [14–16].”
Chitin/chitosan: modifications and their unlimited application potential—an overview (2007, background): “On addition of a Lewis acid such as SnCl4 or TiCl4 to iodo-chitin in nitrobenzene, reactive carbenium species were formed, with which styrene was efficiently graft-copolymerized by a cationic mechanism in the swollen state (Kurita, 2001).”