The age-dependent relation of blood pressure to cognitive function and dementia.

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Epidemiology of Alzheimer's disease: occurrence, determinants, and strategies toward intervention (2009, background): “Antihypertensive treatment may protect against dementia and AD by postponing atherosclerotic process, reducing the number of cerebrovascular lesions, and improving cerebral perfusion.(74) It has also been suggested that some antihypertensive agents (eg, calcium-channel antagonists) may have neuropro”
2007 Guidelines for the Management of Arterial Hypertension: The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC) (2007, background): “For the present time cognitive impairment in hypertensives may be considered as an indication for blood pressure reduction, but additional research in this area is necessary because evidence is preliminary and cognitive dysfunction is present in about 15% of individuals aged 65 years with a 5% preva”
DNA methylation age of blood predicts all-cause mortality in later life (2015, positive): “Specifically, vascular insults, as measured by diabetes and hypertension, which are linked to cognitive decline, dementia, and death [25-27], were not associated with Δage.”