Formation of stress granules inhibits apoptosis by suppressing stress-responsive MAPK pathways

By Kyoko Arimoto, H. Fukuda, S. Imajoh‐ohmi, H. Saito, Mutsuhiro Takekawa. Nature Cell Biology, 2008

615 citations recorded by the source corpus.

Subfields: Cell Biology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/d3744dcdf0a6c1dd78f292c7c663d55a30c8c6e2

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In Molecular Biology

1. C. J. Decker
2. R. Parker
3. Roy Parker
4. J. Buchan
5. P. A. Kiely
6. David R. Adams
7. D. Ron
8. Saumya Jain

Citations in the corpus

• Eukaryotic stress granules: the ins and outs of translation. (2009, background): “This limits MTK1 activation, and apoptosis is avoided (Arimoto et al., 2008).”
• P-bodies and stress granules: possible roles in the control of translation and mRNA degradation. (2012, background): “For example, formation of stress granules may sequester RACK1 away from MAP kinases, thereby limiting signal transduction and apoptosis (Arimoto et al. 2008).”
• RACK1, A multifaceted scaffolding protein: Structure and function (2011, positive): “In response to stress, RACK1 is sequestered into stress granules and inhibits apoptosis by suppressing stressresponsive MAPK pathways [136] Elegent studies carried out by Ohn et al, [137], have revealed that in response to arsenite-induced stress, RACK1 is reversibly modified by O-linked N-acetylglu”