Inflammatory Cytokine-Induced Intercellular Adhesion Molecule-1 and Vascular Cell Adhesion Molecule-1 in Mesenchymal Stem Cells Are Critical for Immunosuppression

By G. Ren, Xin Zhao, Liying Zhang, Jimin Zhang, A. L'Huillier, Weifang Ling, A. Roberts, A. Le, S. Shi, C. Shao and 1 more. Journal of Immunology, 2010

629 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/288345981688346edb72ef8583e16557c5d691c8

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

1. R. Lee
2. Yufang Shi
3. T. Bartosh
4. D. Prockop
5. Ying Wang
6. Hosoon Choi
7. Joni H. Ylöstalo
8. T. Squillaro

Citations in the corpus

• Clinical Trials with Mesenchymal Stem Cells: An Update (2016, background): “Notably, homing-related molecules in general can be upregulated by inflammatory cytokines such as tumor necrosis factor (TNF) and IL-1 (103), suggesting that different inflammation statuses might promote distinct MSC engraftment and therapeutic efficiencies (133).”
• Immunobiology of mesenchymal stem cells (2013, background): “as well as a burst of chemokine and adhesion molecule expression, including CXCR3 ligands, CCR5 ligands, intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1).(48,57) Their concerted action”
• Aggregation of human mesenchymal stromal cells (MSCs) into 3D spheroids enhances their antiinflammatory properties (2010, background): “The potential paracrine effects of the cells was suggested by the observations that the cells in culture secrete a large number of cytokines (9, 10).”