The twilight of immunity: emerging concepts in aging of the immune system

By J. Nikolich-Žugich. Nature Immunology, 2017

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How researchers see this paper

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Dengue and severe dengue (2025, neutral): “Aging affects both the innate and adaptive immune systems (207, 208).”
Human Bone Marrow Assessment by Single Cell RNA Sequencing, Mass Cytometry and Flow Cytometry (2018, background): “It is well established that the T memory cell 189 population increases with increasing age in humans, likely due to response to viral 190 infection (in particular CMV), and this trend was reproduced in our cohort using both 191 scRNAseq and flow cytometry (Figure S2)(14).”
Immunosenescence and Its Hallmarks: How to Oppose Aging Strategically? A Review of Potential Options for Therapeutic Intervention (2019, background): “In fact, aging process more extensively affects acquired immunity than innate immunity (3, 5).”
Mechanisms of SARS-CoV-2 Transmission and Pathogenesis (2020, neutral): “Age-Associated COVID-19 Severity It is widely accepted that the aging process predisposes individuals to certain infectious diseases [68].”