Time evolution of the nanoparticle protein corona.

By E. Casals, Tobias Pfaller, A. Duschl, G. Oostingh, V. Puntes. ACS Nano, 2010

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Molecular Toxicity Mechanism of Nanosilver (2014, background): “[111] Casals E, Pfaller T, Duschl A, et al.”
The evolution of the protein corona around nanoparticles: a test study. (2011, background): “have also shown the transition from a loosely attached protein corona from media containing 10% of fetal bovine serum around gold nanoparticles that over time, evolves toward an irreversible attached protein corona.(10) * Address correspondence to Martin.”
Mechanisms of Silver Nanoparticle Release, Transformation and Toxicity: A Critical Review of Current Knowledge and Recommendations for Future Studies and Applications (2013, background): “Those phenomena were studied on a range of different nanoparticles, also some metallic ones [107,108].”
Interaction of nanoparticles with proteins: relation to bio-reactivity of the nanoparticle (2013, background): “For example, when exposed to blood plasma the nano-bio interface has been reported to change with time due to constant adsorption and desorption of proteins [1].”