Cardiovascular Risk Factors Emerge After Artificial Selection for Low Aerobic Capacity
By Ulrik Wisløff, S. Najjar, Ø. Ellingsen, P. Haram, S. Swoap, Qusai Y Al-Share, M. Fernström, K. Rezaei, S. J. Lee, L. Koch and 1 more. Science, 2005
710 citations recorded by the source corpus.
Subfields: Complementary and alternative medicine, Genetics, Physiology
View Paper: https://www.semanticscholar.org/paper/d1d10cb77ebfa10466e79f4f88c386bb42bcf0bf
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In Physiology
Citations in the corpus
- Hepatic lipotoxicity and the pathogenesis of nonalcoholic steatohepatitis: The central role of nontriglyceride fatty acid metabolites (2010, background): “Rats selected for poor aerobic capacity have been shown to exhibit impaired muscle mitochondrial function and are prone to NAFLD.112,113 The possibility that genetic or acquired mitochondrial defects predispose to both exercise intolerance and NAFLD in humans requires further investigation.”
- Oral administration of vitamin C decreases muscle mitochondrial biogenesis and hampers training-induced adaptations in endurance performance. (2008, background): “These observations are consistent with the role of impaired regulation of mitochondrial function as an important mechanism for low aerobic capacity (19).”