The neutrophil as a cellular source of chemokines

By P. Scapini, José A. Lapinet-Vera, S. Gasperini, F. Calzetti, F. Bazzoni, M. Cassatella. Immunological Reviews, 2000

860 citations recorded by the source corpus.

Subfields: Immunology, Immunology and Allergy, Oncology

View Paper: https://www.semanticscholar.org/paper/d123f773da6ca924d025f9366f97bbc2e28a8899

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Citations in the corpus

Blood-brain barrier pathophysiology in traumatic brain injury (2011, background): “In the injured brain, at least at the early stage after the impact, chemokines appear to be predominantly synthesized by the cerebrovascular endothelium and astrocytes [178]; however, later on, invading neutrophils and monocytes may also contribute to chemokine production in the traumatized brain pa”
Polarization of Tumor-Associated Neutrophil (TAN) Phenotype by TGF-β: “N1” versus “N2” TAN (2009, background): “The level of ICAM-1 surface expression was increased by about 2-fold in the neutrophils of SM16-treated mice, as shown by flow cytometry (7.4% ± 0.1% of neutrophils in control mice versus 12.6% ± 0.8% in SM16-treated mice, p < 0.01). mRNA for VEGF was reduced by 2-fold in the LKR SM16-treated tumors”
Neutrophils, from marrow to microbes. (2010, background): “…more active as phagocytic cells than blood neutrophils (Sørensen et al., 2001) and activate a transcriptional program that results in generation of several chemokines, including IL-8 and Groa (Theilgaard- Mö nch et al., 2004; Scapini et al., 2000, 2005), that recruit additional inflammatory cells.”
The neuro-immune balance in neuropathic pain: involvement of inflammatory immune cells, immune-like glial cells and cytokines. (2010, positive): “…(Zuo et al., 2003), the inflammatory process is perpetuated by the release from neutrophils of mediators chemotactic for macrophages including macrophage inflammatory protein-1α and -1β (MIP-1α andMIP-1β), IL-1β and defensins (Scapini et al., 2000; Welling et al., 1998; WitkoSarsat et al., 2000).”
Acute Chorioamnionitis and Funisitis: Definition, Pathologic Features, and Clinical Significance (2015, background): “potent chemokines for these leukocytes.(213-217) The primary cells and tissues responsible for an intraamniotic inflammatory response include fetal skin, cells that comprise the chorioamniotic membranes, and the umbilical cord.”
Neutrophil-Derived Cytokines: Facts Beyond Expression (2014, background): “As displayed in Figure 1, both human and murine neutrophils may potentially produce several chemokines upon activation, including IL-8/CXCL8, GROα/CXCL1, MIG/CXCL9, IP-10/CXCL10, and ITAC/CXCL11, monocyte chemotactic protein-1 (MCP-1/CCL2), macrophage inflammatory protein-1α (MIP-1α/CCL3) and MIP1β/”
Suppression of Cornea Stromal Fibrosis by Vitamin D (2025, unknown): “After a corneal scrape wound, neutrophils extravasate from the limbal vessels and migrate through the corneal stroma to the site of damage [92,93].”