Mesoangioblast stem cells ameliorate muscle function in dystrophic dogs

By M. Sampaolesi, S. Blot, G. D’Antona, N. Granger, R. Tonlorenzi, A. Innocenzi, P. Mognol, J. Thibaud, B. Galvez, I. Barthélémy and 10 more. Nature, 2006

773 citations recorded by the source corpus.

Subfields: Genetics, Molecular Biology, Surgery

View Paper: https://www.semanticscholar.org/paper/d0fa1a3ee564bf28709646cc6176bf8fbd9eb03e

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Genetics

1. T. Partridge
2. S. Tajbakhsh
3. Michael A. Rudnicki
4. P. Zammit
5. F. Relaix
6. C. Bentzinger

In Molecular Biology

1. T. Partridge
2. S. Tajbakhsh
3. J. Vandooren
4. G. Opdenakker
5. J. Tidball
6. P. E. Van den Steen
7. Michael A. Rudnicki
8. P. Zammit

In Surgery

1. T. Partridge
2. P. Zammit
3. F. Relaix
4. Michael A. Rudnicki

Citations in the corpus

• Biochemistry and molecular biology of gelatinase B or matrix metalloproteinase-9 (MMP-9): The next decade (2013, background): “One of the experimental therapies for muscular dystrophy patients includes transplantation of mesoangioblasts (Minasi et al., 2002; Sampaolesi et al., 2003, 2006).”
• An absolute requirement for Pax7-positive satellite cells in acute injury-induced skeletal muscle regeneration (2011, background): “In fact, the effectiveness of transplanted mesoangioblasts in ameliorating muscle dystrophy in a canine model, has raised considerable hope in human patients (Sampaolesi et al., 2006).”
• Exercise is the real polypill. (2013, background): “This seems to be the case for skeletal muscles, where not only satellite cells but also a variety of resident MSCs (mMSCs) can repair damage (16, 100, 325, 419, 482).”
• Duchenne muscular dystrophy. (2006, positive): “Several groups have been studying the disease in a Golden Retriever dog model, which most accurately simulates the pathology of human DMD(Sampaolesi et al 2006).”
• Regulatory interactions between muscle and the immune system during muscle regeneration. (2010, background): “Stem cells used in these assays were vesselassociated mesangioblasts, which have been previously shown to be capable of contributing to muscle regeneration in dystrophic muscle (94).”
• Pax7-expressing satellite cells are indispensable for adult skeletal muscle regeneration (2011, background): “These include mesoangioblasts, which are associated with blood vessels in mice, dogs and humans (Dellavalle et al., 2007; Sampaolesi et al., 2006; Sampaolesi et al., 2003), and interstitial cells (PICs) which express Pw1 (Peg3 – Mouse Genome Informatics), an imprinted gene involved in regulating…”