Regulation of actin filament assembly by Arp2/3 complex and formins.

By Thomas D. Pollard. Annual Review of Biophysics and Biomolecular Structure, 2007

1,044 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/cfa30f555870c149182c7004d327c9f82d221bb7

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In Cell Biology

Citations in the corpus

Actin stress fibers – assembly, dynamics and biological roles (2012, background): “Rac1 is involved in lamellipodia and membrane ruffle formation by activating the actin nucleating complex Arp2/3, whereas Cdc42 induces filopodia formation by promoting actin polymerization through the formin mDia2 (also known as DIAPH3 and DRF3) (Pollard, 2007).”
Virus entry by macropinocytosis (2009, background): “These regulators include WAVE and Arp2/3, which form nucleation sites for actin polymerizatio”
Actin Structure and Function (2011, neutral): “An important group of ABPs are those that regulate the de novo formation of actin filaments, which include actin filament nucleation and elongation factors (6, 12, 43).”
Cell–matrix adhesion (2007, background): “The matrix rigidity or exogenous tension of collagen gels regulates fibroblast cell migration and cell signaling (Rhee et al., 2007).”
Integrin Structure and Function (2010, background): “Arp2/3 complex has no endogenous actin nucleating activity and must be activated by the Wiskott–Aldrich Syndrome protein (WASP)/Scar family of activator proteins (Pollard 2007).”
Linking actin dynamics and gene transcription to drive cellular motile functions (2010, neutral): “G-actin forms complexes with different ABPs, including the nucleating factors profilin, formins and the actin-related protein 2/3 (ARP2/3) comple”
Genetic and cell biological analysis of integrin outside-in signaling. (2009, background): “However, the isolated Arp2/3 complex has no endogenous actin nucleating activity and must be activated by the Wiskott-Aldrich Syndrome protein (WASP)/Scar family of activator proteins (Pollard 2007).”