Quantitative kinetic analysis of the bacteriophage λ genetic network

By O. Kobiler, A. Rokney, Nir Friedman, D. Court, J. Stavans, A. Oppenheim. 2005

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Cro’s role in the CI–Cro bistable switch is critical for λ’s transition from lysogeny to lytic development (2007, background): “CII also activates the PI promoter for the integrase protein that inserts the genome as a prophage into the host chromosome, and the PAQ promoter that inhibits the production of the late gene activator Q (Kobiler et al. 2005; Court et al. 2007).”
A New Look at Bacteriophage λ Genetic Networks (2006, background): “Since calculations indicate that a cell infected by two phage is sufficient to tip the balance in favor of lysogeny (9, 36 , 37), it is reasonable to expect that more CIII and CII would be made from twice the number of infecting phage, thus enabling the CII-mediated switch.”