Designing Randomized, Controlled Trials Aimed at Preventing or Delaying Functional Decline and Disability in Frail, Older Persons: A Consensus Report

By Luigi Ferrucci, Jack M. Guralnik, Stephanie A. Studenski, L. Fried, G. Cutler, J. Walston. Journal of The American Geriatrics Society, 2004

1,055 citations recorded by the source corpus.

Subfields: Economics and Econometrics, Geriatrics and Gerontology, Physiology

View Paper: https://www.semanticscholar.org/paper/cf702a87b1902a0527ca08787fb64b2d8fa7ea50

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Citations in the corpus

Sarcopenia: Its assessment, etiology, pathogenesis, consequences and future perspectives (2008, background): “Sarcopenia also plays a predominant role in the etiology and pathogenesis of frailty, which is highly predictive of adverse events such as hospitalization, associated morbidity and disability and mortality (215, 216).”
The Identification of Frailty: A Systematic Literature Review (2011, background): “Whether exploring the etiologies and predictors of frailty, or interventions to prevent and treat frailty, researchers need a clear definition to define their study populations and measure their results.(8,9,16) Similarly, policy decisions regarding the distribution of scarce resources to help frail”
Frailty: Emergence and Consequences in Women Aged 65 and Older in the Women's Health Initiative Observational Study (2005, background): “The ability to identify a set of readily measured indicators of frailty can serve as a foundation for further research about the mechanisms of frailty and interventions to modify it.(3) In addition, identification of a set of simply measured indicators could enable clinicians to identify those at ri”
The Effectiveness of Exercise Interventions for the Management of Frailty: A Systematic Review (2011, background): “However, there is broad support for the understanding that frailty is a state of vulnerability, caused by multisystem reduction, ranging in severity from mild to severe, that places the individual at increased risk of adverse health outcomes [2, 3].”
Association of frailty with survival: a systematic literature review. (2013, methodology): “We used the framework proposed by the Interventions on Frailty Working Group to identify criteria of frailty in epidemiologic studies (Ferrucci et al., 2004).”
Geriatric Syndromes: Clinical, Research, and Policy Implications of a Core Geriatric Concept (2007, background): “Although there is not yet a consensus definition, frailty is defined here as impairment in mobility, balance, muscle strength, cognition, nutrition, endurance, and physical activity.(12) Frailty and the other geriatric syndromes may also feedback to result in the development of more risk factors and”
Frailty: an emerging research and clinical paradigm--issues and controversies. (2006, background): “The results of clinical trials testing the effectiveness of treatment for these and other medical conditions cannot be extended to older frail individuals unless frail individuals are included in the trials (68).”
Transitions between frailty states among community-living older persons. (2006, background): “However, some investigators(25) have cautioned that it would be premature to accept the Fried et al definition of frailty as the reference standard, despite evidence supporting its validity, given the clinical complexity of frailty and the omission of potentially important features such as cognitive”
The I.A.N.A. task force on frailty assessment of older people in clinical practice (2008, neutral): “(13) b) American Geriatrics Society /National Institute on Aging Research Conference on Frailty in older adults.”