Inflammatory processes in muscle injury and repair.

By J. Tidball. American Journal of Physiology. Regulatory Integrative and Comparative Physiology, 2005

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Leucocytes, cytokines and satellite cells: what role do they play in muscle damage and regeneration following eccentric exercise? (2012, background): “Reports from various animal models show that exercise-induced muscle damage is linked to inflammation (88,200,274,275,296).”
Aberrant repair and fibrosis development in skeletal muscle (2011, background): “outcome of muscle repair, or alternatively, fibrosis [12,14,17,18].”
Swainson’s thrushes in migratory disposition exhibit reduced immune function (2008, background): “Nonadaptive immunosuppression The observed immunosuppression may be a consequence of a rise in reactive oxygen species (free radicals; ROS) during strenuous exercise.”
The Continuum of Aging and Age-Related Diseases: Common Mechanisms but Different Rates (2018, background): “This early phase is followed by infiltration of M2 macrophages that produce soluble factors that repair the muscle injury and promote regeneration (62).”