The Role of Tumor Stroma in Cancer Progression and Prognosis: Emphasis on Carcinoma-Associated Fibroblasts and Non-small Cell Lung Cancer

By R. Bremnes, T. Dønnem, S. Al-Saad, K. Al-Shibli, S. Andersen, R. Sirera, C. Camps, Inigo Marinez, L. Busund. Journal of Thoracic Oncology, 2011

618 citations recorded by the source corpus.

Subfields: Cell Biology, Molecular Biology, Oncology

View Paper: https://www.semanticscholar.org/paper/ce9fbb7c49c3ecc0810486900ad21b6cecc3a2da

How researchers see this paper

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In Molecular Biology

1. J. Shim
2. Paul Geeleher
3. Nancy J. Cox
4. Bowen Du
5. R. Huang
6. Tero Aittokallio
7. Mehreen Ali

In Oncology

1. J. Shim
2. Bowen Du

Citations in the corpus

• Clinical drug response can be predicted using baseline gene expression levels and in vitro drug sensitivity in cell lines (2014, background): “The cell line training set could also be expanded by including data on cellular sensitivity within different microenvironments and cell lines under different simulated stromal conditions, as it is known that the tumor microenvironment plays a key role in tumor development [47].”
• Targeting Epithelial–Mesenchymal Transition (EMT) to Overcome Drug Resistance in Cancer (2016, background): “Cancer-associated fibroblasts (CAF), a component of tumor stroma, play an important role in supporting the proliferative and invasive behavior of cancer cells through cell–cell interaction or extracellular signaling molecules [60].”