Estrogen receptor interaction with estrogen response elements.

By C. Klinge. Nucleic Acids Research, 2001

1,107 citations recorded by the source corpus.

Subfields: Cancer Research, Genetics, Oncology

View Paper: https://www.semanticscholar.org/paper/cde39c3d182d4147c8230753cf4cf8ee0c6b4439

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cancer Research

1. S. C. Jernigan
2. J. Zhang
3. K. Mattingly
4. K. E. Risinger
5. Carolyn L. Smith
6. B. O’Malley
7. N. Fuentes
8. P. Silveyra

In Genetics

1. Carolyn L. Smith
2. B. O’Malley
3. S. C. Jernigan
4. J. Zhang
5. K. Mattingly
6. K. E. Risinger
7. N. Fuentes
8. P. Silveyra

In Oncology

1. S. C. Jernigan
2. J. Zhang
3. K. Mattingly
4. K. E. Risinger
5. N. Fuentes
6. P. Silveyra
7. Carolyn L. Smith
8. B. O’Malley

Citations in the corpus

• In vitro molecular mechanisms of bisphenol A action. (2007, background): “complex, and depend on the recruitment of tissue-specific co-regulatory factors that differentially affect the interaction of ERs with EREs of different target genes [91,92].”
• Chromosome-wide mapping of estrogen receptor binding reveals long-range regulation requiring the forkhead protein FoxA1. (2005, background): “A consensus 15 base sequence identical to the canonical ERE was present in 49% of all the ER binding sites on chromosomes 21 and 22 (Figure 4B; Klinge, 2001).”
• Estrogen response element-dependent regulation of transcriptional activation of estrogen receptors α and β by coactivators and corepressors (2004, methodology): “ERE correlates with E2-induced transcriptional activity ( Klinge 2001 ), there is not a correlation between ERE occupancy (Kd) and the transcriptional response to the tested coactivators, coregulators, and corepressors in transfected CHO-K1 cells.”
• Estrogen signaling multiple pathways to impact gene transcription. (2006, background): “This “perfect” ERE sequence was shown to function in an orientation- and distance-independent manner, both of which are properties of an enhancer [7, 42].”
• Estrogen synthesis and signaling pathways during ageing: from periphery to brain (2013, background): “This is consistent with the fact that both ERs bind to estrogen responsive elements (EREs) with similar selectivity and affinity [65].”
• Estrogen receptor signaling mechanisms (2019, background): “This complex is then translocated to the nucleus, where it binds to the chromatin at ERE sequences, enhancer regions within or close to promoters, and/or 3’-untranlated regions of target genes (Klinge, 2001).”
• Genome-wide analysis of estrogen receptor binding sites (2006, background): “However, within the list of estrogen receptor binding sites near promoter-proximal regions, we found a number of previously identified estrogen receptor targets, including TFF1 , EBAG9 , TRIM25 (also known as Efp ), ESR1 and prothymosin α ( PTMA ), found using the stringent threshold, and cat”
• Coregulator function: a key to understanding tissue specificity of selective receptor modulators. (2004, background): “For instance, for the 38 estrogen-responsive genes reviewed by Klinge (196), most of the functional EREs located within the promoters or 3Ј-untranslated regions are not the traditional consensus sequence.”