The Arabidopsis GNOM ARF-GEF mediates endosomal recycling, auxin transport, and auxin-dependent plant growth.

By N. Geldner, Nadine Anders, H. Wolters, Jutta Keicher, Wolfgang Kornberger, P. Muller, A. Delbarre, T. Ueda, A. Nakano, G. Jürgens. Cell, 2003

1,153 citations recorded by the source corpus.

Subfields: Cell Biology, Molecular Biology, Plant Science

View Paper: https://www.semanticscholar.org/paper/cdad4235f79f9898a027d5bc7584fbb7e5190c23

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In Cell Biology

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2. York Stierhof

In Molecular Biology

1. Jir□í Friml
2. Ben Scheres
3. René Benjamins
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In Plant Science

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6. Maciek Adamowski
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8. D. Chinchilla

Citations in the corpus

• Rapid, combinatorial analysis of membrane compartments in intact plants with a multicolor marker set. (2009, background): “, 2001), and has become a major tool to manipulate and define plant endosomes (Geldner et al., 2003; Richter et al., 2007).”
• Regulation of phyllotaxis by polar auxin transport (2003, background): “In the root, the subcellular localization of PIN1 is dynamically regulated by GNOM, which is a component of the vesicular cycling mechanis”
• Efflux-dependent auxin gradients establish the apical–basal axis of Arabidopsis (2003, background): “, and that GN encodes a regulator of vesicle trafficking that mediates the subcellular targeting of auxin-transport component”
• Auxin in action: signalling, transport and the control of plant growth and development (2006, background): “org/servlets/TairObject?id=429880&type=gene"> ADP RIBOSYLATION FACTOR-1 itself, can lead to defects in PIN functio”
• CRL4 regulates crown root formation through auxin transport in rice (2008, neutral): “In addition, formation of the lateral root primordia necessitates the re-establishment of cell division and elongation patterns orthogonal to the axis of the primary root in Arabidopsis (Geldner et al. 2003b).”
• FM‐dyes as experimental probes for dissecting vesicle trafficking in living plant cells (2004, background): “Geldner et al. (2003) therefore proposed that GNOM-positive membranes were not located in the secretory pathway, and suggested that they could be components of ‘endosomal’ compartments.”
• Auxin transport routes in plant development (2009, background): “This guanine nucleotide exchange factor for ADP-ribosylation factors (ARF-GEF)-dependent, transcytosis-like PIN1 polarity switch (Kleine-Vehn et al., 2008a) mediates the auxin flow towards the primordium tip, where an auxin maximum is formed.”
• Membrane Dynamics in the Early Secretory Pathway (2007, background): “The target of BFA action—the Sec7-like domain in ARFGEFs—-is the same in animal as in plant cells (Nebenführ et al., 2002; Geldner et al., 2003), but the duration of drug application is important when interpreting its action.”
• Ligand-induced endocytosis of the pattern recognition receptor FLS2 in Arabidopsis. (2006, background): “During plant growth and development, various processes are regulated by polar transport of the phytohormone auxin, which is mediated by a polar distribution of the auxin efflux carrier PIN1 through its trafficking from endosomal compartments (Geldner et al. 2003).”
• PIN-Dependent Auxin Transport: Action, Regulation, and Evolution (2015, background): “A candidate for the protein that may mediate this BFA-sensitive polar delivery of PIN1 is the ARFGEF GNOM. gnom mutants demonstrate severe defects in development, characterized, in extreme cases, by a complete loss of apical-basal body plan (Mayer et al., 1991; Shevell et al., 1994).”
• Regulation of Root Growth by Plant Hormones—Roles for Auxin and Gibberellin (2005, background): “For the classical overview of auxin and root growth, see Scott (1972) ; Feldman (1984) ; Porterfield (2002) ; and Pilet (2002) .”
• Comprehending crystalline β-carotene accumulation by comparing engineered cell models and the natural carotenoid-rich system of citrus (2011, neutral): “Apical generation of PIN polarity is caused by non-polar PIN secretion and clathrin-mediated PIN endocytosis, as well as ARF-GNOM-dependent basal PIN endocytotic recycling (Geldner et al., 2003; Dhonukshe et al., 2007, 2008).”
• Auxin: the looping star in plant development. (2008, background): “In their model the localized auxin sources also provide an explanation for the formation of discontinuous veins, something that is observed in vesicle trafficking mutants such as gnom and van3 (44, 45, 62).”