Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer

By Kai Wang, Junsuo Kan, S. Yuen, S. Shi, K. Chu, S. Law, T. Chan, Zhengyan Kan, Annie S Y Chan, W. Tsui and 11 more. Nature Genetics, 2011

770 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Post operative radiation therapy in endometrial carcinoma : reducing overtreatment and improving quality of life (2013, background): “A similar inverse relationship between TP53 mutations and MSI status was recently found in gastric cancer.(24) The authors hypothesized that this may be explained by alterations in an emerging tumor suppressor gene, ARID1a (component of the SWI/SNF chromatin remodeling complex), that may constitute ”
Cancer epigenetics: from mechanism to therapy. (2012, background): “These efforts have highlighted high-frequency mutations in several SWI/SNF complex members in a range of hematological (Chapman et al., 2011; Morin et al., 2011) and solid malignancies (Gui et al., 2011; Jones et al., 2010; Tan et al., 2011; Varela et al., 2011; Wang et al., 2011).”