Metabolic Diversity of Lichen‐Forming Ascomycetous Fungi: Culturing, Polyketide and Shikimate Metabolite Production, and PKS Genes

By Elfie Stocker-Woergoetter. 2008

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Bioactive lichen metabolites: alpine habitats as an untapped source (2011, background): “Only few lichen compounds are commercially available whereas the thousand known compounds are only partly or not at all investigated for their medicinal potential (Stocker-Wörgötter 2008).”
Lecanoric acid, a secondary lichen substance with antioxidant properties from Umbilicaria antarctica in maritime Antarctica (King George Island) (2009, background): “Lichens synthesize a great variety of secondary metabolites which are often structurally unique, with only a small number of them being found in other fungi and higher plants (Stocker-Wörgötter 2008).”
Intimate bacterial–fungal interaction triggers biosynthesis of archetypal polyketides in Aspergillus nidulans (2009, background): “Interestingly, lecanoric acid is a typical lichen metabolite (16).”