Promoting resistance by the emission of antibiotics from hospitals and households into effluent.

By K. Kümmerer, A. Henninger. Clinical Microbiology and Infection, 2003

596 citations recorded by the source corpus.

Subfields: Applied Microbiology and Biotechnology, Pollution, Water Science and Technology

View Paper: https://www.semanticscholar.org/paper/cd13f6029ff1fe22871ff59813ab349a0b8437e7

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In Applied Microbiology and Biotechnology

In Pollution

In Water Science and Technology

Citations in the corpus

Occurrence of pharmaceutical compounds in urban wastewater: removal, mass load and environmental risk after a secondary treatment--a review. (2012, background): “7/3 5/7/8/8/9.6/10 13/19/20 42/46/48/52/60 89.5/87/−4.4/−13/84/82.5 88.4/98/87/99/92/99 86/92/99.8 99/98/98/97/82 Santos et al., 2007/Santos et al., 2009/Clara et al., 2005a/Roberts and Thomas, 2006/Santos et al., 2009/Radjenovic et al., 2007 Santos et al., 2007/Kimura et al., 2007/Yu et al., 2006/Z”
Correlation of tetracycline and sulfonamide antibiotics with corresponding resistance genes and resistant bacteria in a conventional municipal wastewater treatment plant. (2012, background): “Antibiotics can be only partially metabolized by humans and animals after administration, and the metabolic rate was estimated to be around 30% (Kümmerer and Henninger, 2003).”
Adsorptive removal of antibiotics from water and wastewater: Progress and challenges. (2015, background): “There are over 250 different antibiotic entities registered for use in human and veterinary medicine (Kümmerer and Henninger, 2003).”
Antibiotics in the aquatic environment--a review--part II. (2009, background): “They may reach this range or even exceed MIC50-values in hospital effluent if not only single compounds but groups of compounds acting via the same mechanism are used (Kümmerer and Henninger, 2003).”
Antibacterial resistance worldwide: causes, challenges and responses (2004, background): “Antimicrobials in waste waters are being reported with increasing frequency and are potentially important contributors to the environmental selection of antibiotic-resistant organism”
Antibiotics in the aquatic environment--a review--part I. (2009, background): “Sales of antibiotics varied more than four-fold: France (36.5), Spain (32.4), Portugal (28.8), and Belgium (26.7) had the highest sales, whereas the Netherlands (8.9), Denmark (11.3), Sweden (13.5), Germany (13.6), and Austria (12.4) had the lowest.”
Resistance in the environment. (2004, background): “Antibiotic concentrations calculated and measured in hospital effluents are in the same order of magnitude as the MICs for sensitive pathogenic bacteria.(35) Resistant bacteria may be selected or favoured by antibiotic substances in hospital effluent.”
The presence of pharmaceuticals in the environment due to human use--present knowledge and future challenges. (2009, background): “However, point sources such as hospitals are likely to be of only minor importance (Kümmerer and Henninger, 2003; Heberer and and ilers, ctors, ... rm 3.”