Biological Insights into TCRγδ+ and TCRαβ+ Intraepithelial Lymphocytes Provided by Serial Analysis of Gene Expression (SAGE)

By J. Shires, E. Theodoridis, A. Hayday. 2001

262 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/ccf2852030ca1c1c7c36410d5a5c11677373d431

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In Immunology

Citations in the corpus

Serial Analysis of Gene Expression in Circulating γδ T Cell Subsets Defines Distinct Immunoregulatory Phenotypes and Unexpected Gene Expression Profiles (2003, methodology): “(19) described IEL compared with IELs in the mouse”
The light and dark sides of intestinal intraepithelial lymphocytes (2011, unknown): “The majority of IELs contain abundant cytoplasmic granules for cytotoxic activity, and they can express effector cytokines, such as interferon-γ (IFNγ), interleukin-2 (IL-2), IL-4 or IL-17 (Ref”
γδ T cells: functional plasticity and heterogeneity (2002, background): “The recent finding that γδ iIELs in naive animals constitutively express transcripts of genes that are associated with cytotoxic and immunoregulatory functions and rapidly acquire cytotoxic function after infectio”
Self-reactivity in thymic double-positive cells commits cells to a CD8αα lineage with characteristics of innate immune cells (2004, methodology): “The CD8αα phenotype, expression of the FceRγ signal transduction molecule and NK cell–related transcripts were also detected by SAGE analysis of IEL”
Multivariate Computational Analysis of Gamma Delta T Cell Inhibitory Receptor Signatures Reveals the Divergence of Healthy and ART-Suppressed HIV+ Aging (2018, background): “Also, murine intestinal γδ T cells described as “activated yet resting” expressed very high levels of mRNA for Granzymes A and B (88).”
The transcription factor PLZF (Zbtb16) directs the effector program of the NKT cell lineage (2008, background): “…a mere combination of those already described for conventional naive T cells and their various memory and effector products (Matsuda et al., 2006; Shires et al., 2001) or whether essential signature transcription factors are induced, transiently or permanently, during the thymic development of…”
The inter-relatedness and interdependence of mouse T cell receptor γδ+ and αβ+ cells (2003, background): “Nonetheless, few studies have identified molecular or cellular characteristics that seem to be γδ-specifi”