Gold nanoparticles are taken up by human cells but do not cause acute cytotoxicity.

By E. E. Connor, Judith N. Mwamuka, Anand Gole, C. Murphy, M. D. Wyatt. Small, 2005

2,368 citations recorded by the source corpus.

Subfields: Biomaterials, Electronic, Optical and Magnetic Materials, Materials Chemistry

View Paper: https://www.semanticscholar.org/paper/cbe0b8390b08ca259aba64159268025565ccf362

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Biomaterials

1. C. Murphy
2. Alaaldin M. Alkilany
3. Xiaohua Huang
4. M. El-Sayed
5. I. El-Sayed
6. J. O’Sullivan
7. Jun‐Hyun Kim
8. P. Jain

In Electronic, Optical and Magnetic Materials

1. Xiaohua Huang
2. M. El-Sayed
3. P. Jain
4. C. Murphy
5. I. El-Sayed
6. Alaaldin M. Alkilany
7. E. Dreaden
8. Chunying Chen

In Materials Chemistry

1. Xiaohua Huang
2. M. El-Sayed
3. C. Murphy
4. P. Jain
5. I. El-Sayed
6. Alaaldin M. Alkilany
7. E. Dreaden
8. T. Randall Lee

Citations in the corpus

• Potential of plant as a biological factory to synthesize gold and silver nanoparticles and their applications (2012, background): “It was suggested in some studies that the toxicity of Au nanoparticles was more likely affected by the ligand chemistry (Connor et al. 2005; Pan et al. 2009).”
• A review of the in vivo and in vitro toxicity of silver and gold particulates: Particle attributes and biological mechanisms responsible for the observed toxicity (2010, background): “However, Connor et al. (2005) demonstrated that gold NPs (4, 12, 18 nm) are not internalised by a human leukemia K562 cell line, illustrating that perhaps this is a sizedependent observation, or due to surface modifications.”
• Gold nanorod assisted near-infrared plasmonic photothermal therapy (PPTT) of squamous cell carcinoma in mice. (2008, background): “Noble metal nanoparticles provide remarkable opportunities in these applications due to their inherently low toxicity [31–33] and strongly enhanced optical properties associated with localized surface plasmon resonance (LSPR) [34–36].”
• Thermo- and pH-Responsive Hydrogel-Coated Gold Nanoparticles (2004, background): “This system is characterized by biocompatibility (Connor et al. 2005), the possibility Electronic supplementary material The online version of this article (doi:10.”
• Nanomaterials and nanoparticles: Sources and toxicity (2007, background): “In fact, many types of nanoparticles seem to be non-toxic [58], [59], others can be rendered non-toxic [60], while others appear to have beneficial health effects [61], [62].”
• Particle size-dependent organ distribution of gold nanoparticles after intravenous administration. (2008, background): “It has been reported that human cells can take up gold nanoparticles without cytotoxic effects [11].”