Cell-Penetrating Peptides: From Basic Research to Clinics.

By G. Guidotti, L. Brambilla, D. Rossi. TIPS - Trends in Pharmacological Sciences, 2017

993 citations recorded by the source corpus.

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Application of Light Scattering Techniques to Nanoparticle Characterization and Development (2018, background): “Besides antimicrobial peptides, nanoparticles can also be combined with cell-penetrating peptides (CPPs) (Guidotti et al., 2017).”
Antimicrobial Peptides: Classification, Design, Application and Research Progress in Multiple Fields (2020, methodology): “Computer design includes simple statistical modeling, Structureactivity relationships study (Abdel Monaim et al., 2018), neural networks (Müller et al., 2018), deep learning (Veltri et al., 2018), word embedding (Hamid and Friedberg, 2018) and machine learning.”
Delivering the Messenger: Advances in Technologies for Therapeutic mRNA Delivery. (2019, positive): “77 Although their internalization mechanisms are not fully understood, it is hypothesized that CPPs may promote clustering of the negatively charged glycosaminoglycans on the cell surface, which in turn triggers macropinocytosis and lateral diffusion or directly disrupts the lipid bilayer.”
Traumatic Brain Injuries: Pathophysiology and Potential Therapeutic Targets (2019, background): “To improve the efficiency of cell entry, these proteins can be fused to a peculiar class of proteins known as cell penetrating proteins (CPPs), which are capable of traversing biological membranes and act as cellular delivery vehicles (Koren and Torchilin, 2012; Guidotti et al., 2017).”